SBIR Gateway
SBIR Gateway Bulletin
NIH SBIR 2012-1 Contracts Presolicitation
August 7, 2011
Updated August 18, 2011




The following are proposed topic areas for the NIH 2012-1 SBIR Contracts Solicitation.

National Institutes of Health

National Cancer Institute (NCI)

  • Development of Anticancer Agents
  • Development of Companion Diagnostics
  • Development of Radiation Modulators For Use During Radiotherapy
  • Reformulation of Cancer Therapeutics using Nanotechnology
  • Probing Tumor Microenvironment Using In Vivo Nanotechnology-based Sensors
  • Development of Innovative Algorithms for Processing & Analysis of In Vivo Images
  • Novel Imaging Agents to Expand the Clinical Toolkit for Cancer Diagnosis, Staging, and Treatment
  • Automated Collection, Storage, Analysis, and Reporting Systems for Dietary Images
  • Development of Low Cost, Small Sample Multi-Analyte Technologies for Cancer Diagnosis, Prognosis and Early Detection
  • Simplified Tissue Microarray Instrument For Clinical and Research Settings (NIH Technology Transfer)
  • High Throughput Isolation of Antigen Specific T-cells for Cancer Therapy (NIH Technology Transfer)
  • Generation and Qualification of Site-specific Post-translationally Modified Proteins for Use as Calibrators in Pharmacodynamic (PD) Assays.

National Center For Research Resources (NCRR)

  • Development of an Integrated Automated High Throughput Platform for Large-Scale Genetic and Therapeutic Screening in Zebrafish.

National Heart, Lung And Blood Institute (NHLBI)

  • Development of Induced Pluripotent Stem (iPS) Cell Lines for Use in Cell-based Bioassays
  • Novel Technologies for Powering Ventricular Assist Devices
  • Reagents for Studying Human Lung Cell Biology and Cellular Function
  • Novel Technologies for Assessing Lipoprotein Sub-fractions
  • Computer Generated Diet and Exercise Reminders Promoting Cardiovascular Health
  • Haptoglobin Treatment to Reduce Complications of Sickle Cell Disease
  • Transmit-receive Surface Array Coils for MRI of Patients with Internal Conductive Devices
  • Multilayer-coated Gratings for Phase-Contrast Computed Tomography
  • Wireless Physiologic Telemetry for Interventional MRI
  • Bioabsorbable Stents for Pediatric Pulmonary Artery Stenosis and Aortic Coarctation
  • Electrophysiologic Catheters for Interventional MRI Ablation of Ventricular Tachycardia.

National Institute On Alcohol Abuse And Alcoholism (NIAAA)

  • Discovery and Preclinical Development of Novel Compounds to Treat Alcohol Use Disorders.
  • Development of Novel Compounds to Treat Alcohol Use Disorders.

National Institute Of Diabetes And Digestive And Kidney Diseases (NIDDK)

  • A Low Molecular Weight Thyroid-Stimulating Hormone Receptor Agonist for Thyroid Cancer (NIH TT).

National Institute On Drug Abuse (NIDA)

  • Confirming Compliance with Experimental Pharmacotherapy Treatment of Drug Abuse
  • Development of a Solid Oral Dosage Form for Fenobam
  • Recovery Warrior: Behavioral Activation Video Game for Substance Abuse via a Commercially Available Active & Interactive Gaming Platform (e.g., Wii, Play Station Move, or Xbox Kinect)
  • Highly Effective Methods for Systemic In Vivo Targeted Delivery of shRNAi to the Brain for Treatment of Substance Use Disorders and Other Brain Disorders
  • Feasibility of Development of RNAi-based Therapeutics for Treatment of HIV and HCV Infections in Drug Abusing Populations
  • Smokescreen: Genetic Screening Tool for Tobacco Dependence and Treatment Approaches
  • Feedback-regulated Naloxone Delivery Device to Prevent Opiate Overdose Deaths
  • Drugged Driving: Future Research Directions.

Centers For Disease Control And Prevention (CDC)

Center For Global Health (GCH)

  • The Development of Lateral Flow Immunochromatographic Devices to Detect Antibodies
  • Development of a Blood Donor Screening Test to Prevent Transfusion Transmitted Babesiosis.

National Center On Birth Defects And Developmental Disabilities (NCBDDD)

  • Development of an Assay to Rapidly Determine Folate Insufficiency in the Field.

National Center For Emerging Zoonotic And Infectious Diseases (NCEZID)

  • Vaccine Adverse Event Reporting System (VAERS) Application for Smartphone
  • Development of Rapid, Point-of-Care Tests for Diagnosis of Fungal Infections.

National Center For HIV/AIDs, Viral Hepatitis, STD, And TB Prevention (NCHHSTP)

  • Testing the Efficacy of HIV Prevention Strategies in Nonhuman Primate Models
  • Data Mining Software for Large-Scale Analyses of Infections Caused by Hepatitis Viruses
  • Developing a Location-Based Application to Identify Adolescent-Friendly Health Care Services.

Office Of Public Health Preparedness and Response (OPHPR)

  • Emergency Vehicle Proximity Alert System.





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