SBIR Gateway
SBIR Gateway Bulletin
NIH SBIR 2007-1 Contracts Presolicitation
July 22, 2005




The following are proposed topic areas for the NIH 2007-1 SBIR Contracts Solicitation.

National Institutes of Health

National Cancer Institute (NCI)

  • Development of Molecular Pharmacodynamic Assays for Targeted Therapies;
  • Synthesis of Stable Isotope-Labeled Steroids as Internal Standards for the Measurement of Endogenous Steroid Hormones in Biologic Samples by Liquid Chromatography ? Mass Spectrometry (LC-MS);
  • Quantitative Assay for O6-Carboxymethyl Guanine DNA Adducts;
  • Development of Anti-Cancer Agents;
  • Development of Software Systems to Facilitate the Use of Electronic Data Records in the Collection of Population-Based Cancer Surveillance Data;
  • Develop Automated Methods to Identify Environmental Exposure Patterns in Satellite Imagery Data;
  • Home Centered Coordinated Cancer Care System;
  • Antibody Array for Cancer;
  • Glycan Arrays for Biomarker Discovery and Validation;
  • Development of Clinical Automated Multiplex Affinity Capture Technology for Detecting Low Abundance Cancer-related Proteins/Peptides;
  • Development of Alternative Affinity Capture Reagents for Cancer Proteomics Research;
  • Early Diagnostics Using Nanotechnology-Based Imaging ad Sensing;
  • Multifunctional Therapeutics Based on Nanotechnology.
National Heart, Lung, And Blood Institute (NHLBI)
  • Ultrasonic Wave Transmitter, Transmission Line and Receiver for Interventional MRI;
  • Ultrafine Magnesium Biodegradable Stents for Orphan Disease Applications;
  • Critical Technologies for Ventricular Assist Devices;
  • Production of Generic Modified Hemoglobin.
National Institute On Alcohol Abuse And Alcoholism (NIAAA)
  • Development of Correlational Alcohol-Relevant Database from Mouse or Rat Transcriptome and Proteome.
National Institute Of Child Health And Human Development (NICHD)
  • Development of a User-based Information System for Mobility Needs.
National Institute On Drug Abuse (NIDA)
  • Development Of Science Literacy Materials Or Programs;
  • Development of Novel Drug Delivery Systems for Treatment Medications;
  • Metabolomics in Drug Abuse Research;
  • Marketing Evidence-Based Prevention Interventions for Substance Abuse and Related HIV Prevention;
  • Development of State-of-the-Art Mechanisms for Epidemiological Research;
  • Automation of the Development of Electronic Data Capture (EDC) System for Clinical Trials Data Collection and Management;
  • Development of Practical Training Materials for Evidence-Based Treatment;
  • Develop a Real-Time fMRI Feedback System that Allows Drug Abusers to Control their Cravings and Urges and/or Increase their Self-Control of their Drug Taking;
  • Design and Synthesis of Treatment Agents for Drug Abuse;
  • Mechanisms and Methods to Maximize Data Utilization
National Institute Of Environmental Health Sciences (NIEHS)
  • Gene Expression and Molecular Imaging to Identify Early Biomarkers and Staging of Lung Cancer Following Environmental Exposures;
  • Quantitative Analysis of Protein Expression in Paraffin Embedded Rodent Tissues;
  • High Throughput MRI for Toxicology;
  • Development of an ELISA for Measuring Serum Levels of NAG-1/MIC/GDF15;
  • Identifying Biomarkers to Predict Renal Disease in Rodent Cancer Bioassays
National Institute Of Mental Health (NIMH)
  • Development of Iterative Continuous Clinical Improvement (ICCI) Models for Mental Disorders Utilizing Clinical Trials and other Relevant Research Sources;
  • Families as Research and Treatment Partners: Developing Evidence Based Decision Aids for Mental Health Treatment Decisions
Centers For Disease Control And Prevention (CDC)

Immunization Safety Office (ISO)

  • Develop Methods to Enhance Administration of Vaccines, Including Live Virus Vaccines, Through the Respiratory Track;
  • Disposable-Cartridge Jet Injector Technology
National Center For Chronic Disease Prevention And Health Promotion (NCCDPHP)
  • Development and Evaluation of Eyewear for Citrus Workers;
  • Linking GIS Technology with Essential Public Health Services;
  • Tools to Enhance the Utilization of Tobacco Cessation Quitlines
National Center For HIV, STD And TB Prevention (NCHSTP)
  • Development of Novel Genotyping Procedures for Mycobacterium Tuberculosis;
  • New Laboratory Tests for Tuberculosis and Detection of Drug Resistance;
  • Development of a Novel Information System for Remote TB Control and Prevention Programs
National Center On Birth Defects And Developmental Disabilities (NCBDDD)
  • Generic Targeting of Thrombotic Risk





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